In this diploma the thesis was to make the conceptual project of manufacturing system for the following manufacturing program: axle with gear (qA = 52 000 pcs/year), axle (qB = 40 000 pcs/year), engine block carrier (qC = 50 000 pcs/year), housing (qD = 37 000 pcs/year), cover (qE = 45 000 pcs/year). In this paper was made the analysis of constructional, technological and manufacturing characteristics followed by a technological treatment plan. Given the complexity and the large amount of default workpieces, universal, flexibility and specialized production equipment will be used. Using the process method, the grouping of workpieces was performed and has four production systems were selected, one two-subject production system (AB manufacutring system) and three one–subject production system (C, D and E manufacturing system). On the basis of the selection of the transport system and the order of processing, a graphical representation of the production cycle, the layout of each production system and the processing of the hodogram for each work was made. At the end of this diploma thesis, the method of producing simulations of defined production systems is presented. For the simulation, Plant Simulation (Siemens PLM Software) was used. By designing this conceptual project, all problems of designing the production system and the possibility to solve the problem in several ways with the aim of achieving the optimal production system were considered.