This paper describes the process of absorption of wavelengths of light in photo acceptors, on which photo biomodulation is based, lists the applications of photo biomodulation in medicine in general, and explains the methods, studies and possible applications of brain photo biomodulation. Furthermore, a commercial device for brain photo biomodulation is shown, and some parameters that are crucial in performing the proper photo biomodulation treatment are explained. After that, a circuit was designed and the values of the required elements were calculated and selected, circuit for generating a rectangular duty cycle waveform of 50% was realized, with a possible choice between three frequencies of modulating the supply voltage and current for the near-infrared LED-s. LED clusters were implemented by connecting LED-s in series to reduce losses and eliminate the need to adjust the supply voltage, which were then connected in parallel. All modules were mounted on the "Ultracortex IV" helmet as a load-bearing structure, the clusters are positioned in the necessary places above the desired parts of the brain to be stimulated, and the power is provided by using portable USB power because of its simplicity and ease of use. Measurements were made on two persons and were performed with two different brain states, a relaxed condition using 10 Hz photo stimulation and a focused condition using 20 Hz photo stimulation, measuring the brain's EEG signal before and during the brain photo stimulation. Afterwards, the measured EEG signals were processed to obtain the frequency spectrum of before and during photo stimulation, which were compared to conclude if photo biomodulation interferes with the measurement of EEG signals and if there is an effect on brain function through the spectrum of EEG signals. Photo biomodulation was considered not to have interfered with EEG measurement, and a significant effect of photo biomodulation on the frequency spectrum of the EEG signal was observed in one subjec